Sample Holder for Crystal Growth, in situ Ligand Soaking and in situ Data Collection with a Robot Assisted Sample Mounting
Shipping: shipped at ambient temperature
Storage Conditions: store at ambient temperature
Shelf Life: n/a
Sample holder for crystal growth, any necessary crystal soaking and X-ray data collection without the need of crystal manipulation or mounting, compatible with SPINE standard magnetic CryoVials and robot assisted sample mounting
The XtalTool HT is a patent-pending sample holder consisting of a plastic support with an outer transparent COC film and an inner X-ray transparent yellow polyimide film with 5 μm pores. The design allows the setup of two crystallization drops on one XtalTool HT. Crystal growth can be monitored either by a transmission microscope or an automated inspection system. All intended manipulative steps on the crystal are carried out in-situ. Before data collection the outer ring can easily be broken off at the designated respective break points. Mounted on an XtalTool Base, the XtalTool HT then fits into a SPINE standard magnetic CryoVial and thereby facilitates robot assisted sample mounting. Its geometry meets the 18 mm SPINE standard and it’s compatible with most synchrotron and in-house beamlines dedicated to macromolecular crystallography.
20 XtalTool HT Sample Holder (18 mm)
1 XtalTool HT Dummy Sample Holder to test individual robot compatibility
The XtalTool HT was developed by HZB MX-group at BESSY II (AG Weiss).
Please click the black arrow on the right to expand the citation list. Click publication title for the full text.
Shilova et al. (2020) Current status and future opportunities for serial crystallography at MAX IV Laboratory. J. Synchrotron Rad. 27:1095.
Feiler et al. (2019) An All-in-one Sample Holder for Macromolecular X-ray Crystallography with Minimal Background Scattering. J. Vis. Exp. 149:e59722.