The 2nd generation of MiTeGen's Cryo-EM pucks has enhanced features, which make them superior to other cryo-EM pucks on the market. They contain magnets in the bottom of the pucks for strong puck retention but easy removal from the shelves of the Cryo-EM Puck Shipping and Storage Canes. A front grabbing tong location for Cryo-EM Puck Grasping Tongs makes puck handling even more secure. Custom 2D barcoding and puck serialization allow advanced sample tracking, a multi-color option completes sample organization and tracking. Each puck has 12 numbered well locations with easy-access tweezer notches for Cryo-EM Grid Boxes.