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96 Well Plates - MRC 2-well and 3-well Plates

MRC 3 Well Plate

The SWISSCI MRC 2 Well and 3 Well Crystallization Plates are designed in the 96 well plate format with either 2 or 3 protein wells per reservoir well. They were developed in collaboration with experienced protein crystallographers, e.g. the MRC Laboratory of Molecular Biology (Cambridge, UK).
Both plates offer unique properties that make it ideal for both nanolitre crystallization screening and microliter optimization alike. They are available in two different materials, i.e. polystyrene and an optically superior polymer (UVP).

2 Well Plate Features

MRC 2 Well Plate Scheme

  • Plate with 2 wells for each sample
  • 192 optical wells offer twice the number of experimental constructions
  • Easy to fill 96-well structure - typically 85 µl per buffer well
  • Standard SBS form for automation
  • Microscopic identifier within wells, simplifying the orientation under the microscope
  • Wells can be individually sealed with a perfectly flat upper surface
  • UVXPO is a new polymer mixture that allows to view crystals in UV, polar and visible light with uniform (zero) background when using cross polarised light

 

3 Well Plate Features

MRC 3 Well Plate Scheme

  • Plate with 3 wells for each sample
  • Triplicates allow for 288 constructs per plate
  • Easy to fill 96-well structure - typically 30 µl per buffer well
  • Standard SBS form for automation
  • Microscopic identifier within wells, simplifying the orientation under the microscope
  • Wells can be individually sealed with a perfectly flat upper surface
  • The profile allows for easier storage

 

Selected Literature Citations of MRC Plates

  • Shneider et al. (2013) PAAR-repeat proteins sharpen and diversify the Type VI secretion system spike. Nature 500:350.
  • Mailliet et al. (2011) Spectroscopy and a High-Resolution Crystal Structure of Tyr263 Mutants of Cyanobacterial Phytochrome Cph1. J. Molecular Biol. 413(1):115.