Dibenzocyclooctyne (DBCO)*-containing (desthio) biotinylation reagents can be used for the labeling of Azide-tagged biomolecules via Cu(I)-free strain-promoted Alkyne-Azide Click Chemistry (SPAAC).
A number of (desthio) biotinylation reagents with
Label | DBCO |
---|---|
Biotin | DBCO-PEG4-Biotin Sulfo-DBCO-Biotin |
Biotin with chemically cleavable linker | Diazo Biotin-DBCO Dde Biotin-DBCO |
Biotin with photocleavable linker | Photocleavable Biotin-DBCO Photocleavable Biotin-Sulfo-DBCO |
Desthiobiotin | DBCO-PEG4-Desthiobiotin |