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AzT, Zidovudine, Azidothymidine


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N-DN-1774-100 100 mg 50,51 Add to Basket/Quote Add to Notepad
Structural formula of 3'-Azido-2',3'-dideoxythymidine (AzT, Zidovudine, Azidothymidine, 1-(3-Azido-2,3-dideoxy-beta-D-ribofuranosyl)-5-methylpyrimidine-2,4-(1H,3H)-dione)
Structural formula of 3'-Azido-2',3'-dideoxythymidine

For research use only!

Shipping: shipped at ambient temperature

Storage Conditions: store at -20 °C

Shelf Life: 30 months after date of delivery

Molecular Formula: C10H13N5O4

Molecular Weight: 267.24 g/mol

CAS#: 30516-87-1

Purity: ≥ 98 % (HPLC)

Form: white crystalline powder

Solubility: methanol

Selected References:
Tornevik et al. (1995) Cytotoxicity of 3’-azido-3’-deoxythymidine correlates with 3’-azidothymidine-5’-monophosphate (AZTMP) levels, whereas anti-human immunodeficiency virus (HIV) activity correlates with 3’-azidothymidine-5’-triphosphate (AZTTP) levels in cultured CEM T-lymphoblastoid cells. Biochem. Pharmacol 49:829.
Hall et al. (1994) 3’-Azido-3’-deoxythymidine potently inhibits protein glycosylation. A novel mechanism for AZT cytotoxicity. J. Biol. Chem. 269:14355.