Azide-containing Bifunctional Reagents

Azide-containing bifunctional reagents are suitable for the introduction of

a functional group to terminal Alkyne-tagged or strained Alkyne (e.g. DBCO)-tagged molecules via Cu(I)-catalyzed Alknye-Azide (CUAAC) or Cu(I)-free strain-promoted Alkyne-Azide Click Chemistry (SPAAC) reaction, respectively
an Azide group to various targets e.g. via NHS Ester- or Maleimide-based chemistry

Table 1: Available Azide-containing Bifunctional Reagents

Functional Group	Azide
NHS ester	Azido-PEG₄-NHS ester Azidoacetic Acid NHS ester
Maleimide	Azido-PEG₃-Maleimide
Acid (-COOH)	Azido-PEG₄-Acid
Amine (-NH₂)	Azido-PEG₃-Amine Azido-Propylamine Picolyl-Azide-Amine (HCl salt)