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Azide-containing Bifunctional Reagents

Azide-containing bifunctional reagents are suitable for the introduction of

  • a functional group to terminal Alkyne-tagged or strained Alkyne (e.g. DBCO)-tagged molecules via Cu(I)-catalyzed Alknye-Azide (CUAAC) or Cu(I)-free strain-promoted Alkyne-Azide Click Chemistry (SPAAC) reaction, respectively
  • an Azide group to various targets e.g. via NHS Ester- or Maleimide-based chemistry


Table 1: Available Azide-containing Bifunctional Reagents