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5/6-Carboxyrhodamine 110-PEG4-Alkyne

Abs/Em = 501/525 nm

Acetylene-Fluor 488

Cat. No. Amount Price (EUR) Buy / Note
CLK-TA106-1 1 mg 135,70 Add to Basket/Quote Add to Notepad
CLK-TA106-5 5 x 1 mg 320,50 Add to Basket/Quote Add to Notepad
CLK-TA106-25 25 mg 1.030,00 Add to Basket/Quote Add to Notepad
Structural formula of 5/6-Carboxyrhodamine 110-PEG4-Alkyne (Abs/Em = 501/525 nm)
Structural formula of 5/6-Carboxyrhodamine 110-PEG4-Alkyne
excitation and emission spectrum of 5/6-Carboxyrhodamine 110
excitation and emission spectrum of 5/6-Carboxyrhodamine 110

For general laboratory use.

Shipping: shipped at ambient temperature

Storage Conditions: store at -20 °C

Shelf Life: 12 months after date of delivery

Molecular Formula: C32H33N3O8

Molecular Weight: 587.62 g/mol

Exact Mass: 587.23 g/mol

Purity: ≥ 90 % (HPLC)

Form: solid

Color: dark red

Solubility: DMF, DMSO, MeOH

Spectroscopic Properties: λabs 501 nm, λem 525 nm, ε 74.0 L mmol-1 cm-1 (in MeOH)

Description:
With excitation maximum at 501 nm, the acetylene - carboxyrhodamine 110 conjugate is an excellent match to the intense 488 nm spectral line of the argon ion laser commonly used in many confocal laser-scanning microscopes. Carboxyrhodamine 110-PEG4-alkyne is an excellent green fluorescent rhodamine dye. The conjugate has better solubility than the parent dye carboxyrhodamine and its long PEG4 spacer should reduce any steric effect of the dye on the molecule to be labeled. Carboxyrhodamine 110 and its derivatives are, in general, significantly more photostable than any other known green fluorescent dyes including Alexa 488. In addition, the fluorescence of the acetylene-PEG4-carboxyrhodamine 110 conjugate is completely insensitive to pH between 4 and 9. Unlike Alexa 488, which is readily degraded under alkaline condition, carboxyrhodamine 110 and its derivatives are highly stable under both acidic and basic conditions. As a result, carboxyrhodamine 110 and its derivatives are superior alternatives to other green fluorescent dyes.

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