Alkyne-containing (Desthio) Biotinylation Reagents

Alkyne-containing (desthio) biotinylation reagents can be used for the labeling of Azide-tagged biomolecules via a Cu(I)-catalyzed Azide-Alkyne Click Chemistry reaction (CuAAC).

A number of (desthio) biotinylation reagents with

improved solubility & detection characteristics (PEG-linker for increased molecule solubility & optimal streptavidin binding)

different cleavability characteristics (chemically or photocleavable linker)

are available to fit specific application & molecule requirements.

Click Chemistry background information

CLICKable (Desthio)Biotinylation Reagents

Table 1: Available Alkyne-containing (Desthio) Biotinylation Reagents

Label	Alkyne
Biotin	Acetylene-PEG₄-Biotin
Biotin with chemically cleavable linker	Diazo Biotin-Alkyne Dde Biotin-Alkyne Diol Biotin-Alkyne
Biotin with photocleavable linker	Photocleavable Biotin-Alkyne
Desthiobiotin	Acetylene-PEG₄-Desthiobiotin

Products & Ordering

Acetylene-PEG₄-Biotin CLK-TA105

Diazo Biotin-Alkyne CLK-1042

Dde Biotin-Alkyne CLK-1137

Acetylene-PEG₄-Desthiobiotin CLK-1109

Photocleavable Biotin-Alkyne CLK-1118

Alkyne-containing (Desthio) Biotinylation Reagents

Table 1: Available Alkyne-containing (Desthio) Biotinylation Reagents

Products & Ordering

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