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Alkyne Magnetic Beads

Alkyne Magnetic Beads are suitable to covalently capture Azide-tagged biomolecules onto magnetic beads by a Cu(I)-catalyzed Azide-Alkyne Click chemistry reaction (CuAAC).

The proteins of interest need to be metabolically, enzymatically or chemically azide-tagged. Subsequently, the Alkyne Magnetic Beads containing the covalently attached proteins can be washed with high stringency, virtually eliminating any non-specifically bound proteins.