(2-EA-NAD+)
Cat. No. | Amount | Price (EUR) | Buy / Note |
---|---|---|---|
CLK-043 | 20 μl (10 mM) | 278,10 | Add to Basket/Quote Add to Notepad |
For research use only!
Shipping: shipped on dry ice
Storage Conditions: store at -20 °C
Shelf Life: 12 months after date of delivery
Molecular Formula: C23H28N7O14P2 (cation)
Molecular Weight: 688.46 g/mol (cation)
Exact Mass: 688.12 g/mol (cation)
Form: clear aqueous solution
Concentration: 10 mM - 11 mM
Applications:
in vitro ADP-Ribosylation of proteins[1](compound 1)
The resulting alkyne-functionalized protein[1,2] can subsequently be processed via Cu(I)-catalyzed (azide-alkyne) click chemistry that offers the choice
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Product Citations:
Please click the black arrow on the right to expand the citation list. Click publication title for the full text.
Selected References:
[1] Wang et al. (2014) Chain-Terminating and Clickable NAD+ analogues for labeling the target proteins of ADP-Ribosyltransferases. Angew. Chem. Int. Ed. 53:8159.
[2] Lin et al. (2012) Labeling substrate proteins of Poly (ADP-ribose) polymerase with Clickable NAD analog. Curr. Prot. in Chem. Biol. 4:19.
[3] Presolski et al. (2011) Copper-Catalyzed Azide-Alkyne Click Chemistry for Bioconjugation. Current Protocols in Chemical Biology 3:153.
[4] Hong et al. (2011) Analysis and Optimization of Copper-Catalyzed Azide-Alkyne Cycloaddition for Bioconjugation. Angew. Chem. Int. Ed. 48:9879.