For research use only!
Shipping: shipped on dry ice
Storage Conditions: store at -20 °C
Shelf Life: 12 months after date of delivery
Molecular Formula: C23H28N7O14P2 (cation)
Molecular Weight: 688.46 g/mol (cation)
Form: clear aqueous solution
Concentration: 10 mM - 11 mM
in vitro ADP-Ribosylation of proteins(compound 1)
The resulting alkyne-functionalized protein[1,2] can subsequently be processed via Cu(I)-catalyzed (azide-alkyne) click chemistry that offers the choice
 Wang et al. (2014) Chain-Terminating and Clickable NAD+ analogues for labeling the target proteins of ADP-Ribosyltransferases. Angew. Chem. Int. Ed. 53:8159.
 Lin et al. (2012) Labeling substrate proteins of Poly (ADP-ribose) polymerase with Clickable NAD analog. Curr. Prot. in Chem. Biol. 4:19.
 Presolski et al. (2011) Copper-Catalyzed Azide-Alkyne Click Chemistry for Bioconjugation. Current Protocols in Chemical Biology 3:153.
 Hong et al. (2011) Analysis and Optimization of Copper-Catalyzed Azide-Alkyne Cycloaddition for Bioconjugation. Angew. Chem. Int. Ed. 48:9879.