* In this issue:

(1) JBS Floppy Choppy – The most successful crystallization rescue strategy!
(2) JBS Black Light – Let your crystal glow!
(3) Crystallization Model Proteins – Easy and reproducible crystallization
(4) MiTeGen Loops – Too fragile? Try the new more stable high-throughput (HT) version

Please click here if this newsletter is not displayed properly!

Important note: If you have questions, comments or want to get in contact with us directly, please DO NOT reply to this newsletter. Please send your inquiry to info@jenabioscience.com.

JBS Floppy-Choppy is the rescue kit for proteins which are recalcitrant to crystallization. It enables you to modify your protein by in situ proteolysis to improve its crystallization behavior.

Just add trace amounts of our Floppy-Choppy-Proteases to the protein solution immediately prior to crystallization. The experiment can be set up without evaluating the efficacy of proteolysis, without stopping the proteolysis reaction and without purification of any proteolyzed protein fragments. So it is very straightforward.

Do you want to test it? Then go to www.jenabioscience.com/cms/en/1/catalog/1357/

JBS Black Light is a nonspecific fluorescent crystal dye used for the detection of protein crystals in crystallization trials. The fluorescence signal can be exploited to contrast protein crystals above background artifacts and enables the detection of microcrystals, even if they are located under a protein skin. Thus, the dye is suitable for automatic crystal detection.

Find more details on our website at www.jenabioscience.com/cms/en/1/catalog/1296/

Our Crystallization Model Proteins can be utilized in crystallization experiments as well as for crystallization training and demos.

We offer 4 proteins which can be easily crystallized within days as lyophilized powder or in a stabilization buffer:

• Lysozyme (Chicken egg white)
• Lipase B (Candida antarctica)
• Xylanase (Trichoderma longibrachiatum)
• Proteinase K (Tritirachium album)

More information can be found at www.jenabioscience.com/cms/en/1/catalog/1351/

MicroLoop™ Mounts provide a superior tool in a familiar format for manipulating and mounting protein/small molecule crystals and many other small fragile samples.

Choose between two film thicknesses: MiTeGen's standard 10 µm for the lowest background scatter, and HT thickness 18 µm for improved durability and rigidity in high-throughput applications.

The elongated sample apertures of the MicroLoops E™ are particularly suitable for needle or rodshaped samples. Choose between Vertical, Horizontal and Inclined aperture MicroLoops E™.

MicroLoops LD™ have a computer-optimized design with longer, thinner necks to minimize disturbance when inserted and withdrawn from small liquid drops. Thick polymer in the neck region makes these mounts rigid in, e.g., a cold gas stream, and thin polymer in the loop region ensures the lowest possible background scatter in X-ray diffraction applications. The world's most advanced loop design.

Check www.jenabioscience.com/cms/en/1/browse/1320/ to view all available designs.

If you wish not to receive further email newsletters from us, please reply to this E-mail with the subject "UNSUBSCRIBE" or unsubscribe via the form at our website at www.jenabioscience.com.