* In this issue:

(1) Pi-minimal Screen & Pi-PEG Screen – Incomplete factorial design for diversity of crystallization conditions!
(2) Dual-Thickness MicroMounts – Superior features unlike any other mount!
(3) High-throughput Crystal Former – Harness the power of diffusive mixing!

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The Pi-minimal Screen and the Pi-PEG Screen were developed at the MRC Laboratory of Molecular Biology (Cambridge, UK) for efficient crystallization screening of soluble proteins and integral membrane proteins, respectively [1]. Both screens are based on incomplete factorial design.

The unique formulation of both screens was generated following a strategy named Pi sampling^[1] in order to create novel combinations of precipitants, buffers and additives across a standard 96-condition plate layout. Thus, the diversity amongst the crystallization conditions is ideal for initial screening.

Find more about the formulation, e.g. the employed buffer systems, of the Pi-minimal Screen at: www.jenabioscience.com/cms/en/1/catalog/1620/

Benefit from the experience of membrane protein crystallization at the MRC and read more about the Pi-PEG Screen under: www.jenabioscience.com/cms/en/1/catalog/1621/

Utilizing advanced proprietary micro-fabrication processes, the Dual-Thickness MicroMounts have a thick, semi-rigid body and a thin, highly X-ray transparent crystal-receiving aperture. This dual thickness maximizes durability and rigidity, while maintaining the ultra-low X-ray background scatter that original MicroMounts™ are known for.

Benefits:

Lowest X-ray Background Greater Rigidity Easier Harvesting

Lower Vibration Easier Auto-Centering Maximum Durability

You find more information under: www.jenabioscience.com/cms/en/1/catalog/1643/

The new High-throughput Crystal Former is now available with 96-microchannels arranged on a SBS-footprint plate.

Like the original Crystal former, the microfluidic device exploits favorable physical conditions for straightforward crystal growth occurring at the microscale.

Read more about the High-throughput Crystal Former and other available Crystal Former formats under:

www.jenabioscience.com/cms/en/1/catalog/1307/

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