home
           
   
         Special Issue – SCNAC XV, Český Krumlov
   
       
       
  
   
    Please click here if this newsletter is not displayed properly!

Important note: If you have questions, comments or want to get in contact with us directly, please DO NOT reply to this newsletter. Please send your inquiry to info@jenabioscience.com.
   
       
  
   
    A big "Thank You!"   
   

A big "Thank you!" goes to the organizers who made the SCNAC XV meeting in Český Krumlov such a great success!

It was a real pleasure to talk to so many participants. We had a wonderful time and many fruitful discussions!


Check out all the pictures we took at

www.jenabioscience.com/pix/SCNAC_2011/



   
   Copper-free Click Chemistry
   


Conventional "Click Chemistry" requires the presence of a Cu(I) catalyst that is toxic to most organisms and thus, prevents its use in many biological systems.

The novel Copper-free Click Chemistry is based on the reaction of a diarylcyclooctyne (DBCO) moiety with an azide-labeled reaction partner, known as strain-promoted alkyne azide cycloaddition (SPAAC). This new "Click Chemistry" is very fast at room temperature and does not require a cytotoxic Cu(I) catalyst. Diarylcyclooctynes are thermostable with very narrow and specific reactivity toward azides, resulting in almost quantitative yields of stable triazoles.

Cu(I)-free ligation reaction scheme: Diarylcyclooctyne-activated biomolecule A reacts with azide-activated biomolecule B without Cu(I) in aqueous conditions to form a stable triazole

Jena Bioscience's new product line for Copper-free Click Chemistry contains:

Find all our Click Chemistry products (also including reagents for conventional Cu-catalyzed click reactions) at:

www.jenabioscience.com/cms/en/1/browse/1379/


   
   On-stock Nucleotide analogs and Custom Synthesis of Nucleotides
   


Jena Bioscience is the leading supplier for nucleotides and their analogs! We have more than 1.000 of natural and modified nucleotides available on stock.

Modified Nucleotides
Modified nucleotide analogs, such as non-hydrolyzable derivatives, nucleotides containing fluorescent groups or halogen atoms and much more

Non-modified Nucleotides
Unmodified NTPs, dNTPs and ddNTPs for applications such as in-vitro transcription, PCR, sequencing...

Nucleotide Libraries & Kits
Libraries of Nucleotide analogs for drug screening and nucleotide kits for a plethora of applications

Nucleosides
Modified nucleoside analogs (i.e. nucleobase linked to a sugar moiety but lacking the phosphate groups)

In addition, with our pre-made building blocks and in-house expertise we manufacture even the most exotic nucleotide analog from the mg to kg scale in a Custom Synthesis, at conditions that are affordable even for academic customers. Find more information in the PDF file below:

      Custom Synthesis


Find all information about our portfolio of Nucleosides, Nucleotides and their Analogs on our website at

www.jenabioscience.com/cms/en/1/browse/106/


   
    Jena Bioscience is your #1 Reagent Supplier!
   


Jena Bioscience is your one-stop-shop for all life science reagents. Check out our complete product portfolio at


www.jenabioscience.com

Jena Bioscience offers more than Nucleotide Analogs and Click Chemistry products: Macromolecular Crystallography accessories, Protein Expression products as well as Affinity Chromatography and Molecular Biology solutions make us your first choice for all life science consumables – at prices that will help to cut your costs significantly.




   
   

If you wish not to receive further email newsletters from us, please reply to this E-mail with the subject "UNSUBSCRIBE" or unsubscribe via the form at our website at www.jenabioscience.com.
 

   
   
   
    Responsible for content / Imprint   
   
Jena Bioscience GmbH
Loebstedter Str. 80
07749 Jena
Germany

Phone:+49 – 3641 – 6285 000
Fax: +49 – 3641 – 6285 100
E-Mail: info@jenabioscience.com

Register Court: Amtsgericht Jena, HRB 207171
VAT No.: DE 195825742

Managing Directors:
Thomas Billert
Dr. Mathias Grün
   
           
    www.jenabioscience.com   
           
      © 2011 Jena Bioscience GmbH - Imprint