Special Issue – SCNAC XV, Český Krumlov
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    A big "Thank You!"   

A big "Thank you!" goes to the organizers who made the SCNAC XV meeting in Český Krumlov such a great success!

It was a real pleasure to talk to so many participants. We had a wonderful time and many fruitful discussions!

Check out all the pictures we took at


   Copper-free Click Chemistry

Conventional "Click Chemistry" requires the presence of a Cu(I) catalyst that is toxic to most organisms and thus, prevents its use in many biological systems.

The novel Copper-free Click Chemistry is based on the reaction of a diarylcyclooctyne (DBCO) moiety with an azide-labeled reaction partner, known as strain-promoted alkyne azide cycloaddition (SPAAC). This new "Click Chemistry" is very fast at room temperature and does not require a cytotoxic Cu(I) catalyst. Diarylcyclooctynes are thermostable with very narrow and specific reactivity toward azides, resulting in almost quantitative yields of stable triazoles.

Cu(I)-free ligation reaction scheme: Diarylcyclooctyne-activated biomolecule A reacts with azide-activated biomolecule B without Cu(I) in aqueous conditions to form a stable triazole

Jena Bioscience's new product line for Copper-free Click Chemistry contains:
  • Non-Fluorescent Azides
  • Biotin Azides
  • PEG and Spacer Azides
  • Azides of Amino Acids
  • Azides of Fluorescent Dyes
  • Azides of Quencher Dyes
  • Nucleotide Azides

Find all our Click Chemistry products (also including reagents for conventional Cu-catalyzed click reactions) at:


   On-stock Nucleotide analogs and Custom Synthesis of Nucleotides

Jena Bioscience is the leading supplier for nucleotides and their analogs! We have more than 1.000 of natural and modified nucleotides available on stock.

Modified Nucleotides
Modified nucleotide analogs, such as non-hydrolyzable derivatives, nucleotides containing fluorescent groups or halogen atoms and much more

Non-modified Nucleotides
Unmodified NTPs, dNTPs and ddNTPs for applications such as in-vitro transcription, PCR, sequencing...

Nucleotide Libraries & Kits
Libraries of Nucleotide analogs for drug screening and nucleotide kits for a plethora of applications

Modified nucleoside analogs (i.e. nucleobase linked to a sugar moiety but lacking the phosphate groups)

In addition, with our pre-made building blocks and in-house expertise we manufacture even the most exotic nucleotide analog from the mg to kg scale in a Custom Synthesis, at conditions that are affordable even for academic customers. Find more information in the PDF file below:

      Custom Synthesis

Find all information about our portfolio of Nucleosides, Nucleotides and their Analogs on our website at


    Jena Bioscience is your #1 Reagent Supplier!

Jena Bioscience is your one-stop-shop for all life science reagents. Check out our complete product portfolio at


Jena Bioscience offers more than Nucleotide Analogs and Click Chemistry products: Macromolecular Crystallography accessories, Protein Expression products as well as Affinity Chromatography and Molecular Biology solutions make us your first choice for all life science consumables – at prices that will help to cut your costs significantly.


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