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Important note: If you have questions, comments or want to get in contact with us directly, please DO NOT reply to this newsletter. Please send your inquiry to info@jenabioscience.com. |
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| A big "Thank You!" | ||||||
A big "Thank you!" goes to the organizers who made the SCNAC XV meeting in Český Krumlov such a great success!
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| Copper-free Click Chemistry | ||||||
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The novel Copper-free Click Chemistry is based on the reaction of a diarylcyclooctyne (DBCO) moiety with an azide-labeled reaction partner, known as strain-promoted alkyne azide cycloaddition (SPAAC). This new "Click Chemistry" is very fast at room temperature and does not require a cytotoxic Cu(I) catalyst. Diarylcyclooctynes are thermostable with very narrow and specific reactivity toward azides, resulting in almost quantitative yields of stable triazoles.
Cu(I)-free ligation reaction scheme: Diarylcyclooctyne-activated biomolecule A reacts with azide-activated biomolecule B without Cu(I) in aqueous conditions to form a stable triazole
Jena Bioscience's new product line for Copper-free Click Chemistry contains:
Find all our Click Chemistry products (also including reagents for conventional Cu-catalyzed click reactions) at:
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| On-stock Nucleotide analogs and Custom Synthesis of Nucleotides | ||||||
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Modified NucleotidesModified nucleotide analogs, such as non-hydrolyzable derivatives, nucleotides containing fluorescent groups or halogen atoms and much more
Non-modified Nucleotides Unmodified NTPs, dNTPs and ddNTPs for applications such as in-vitro transcription, PCR, sequencing...
Nucleotide Libraries & Kits Libraries of Nucleotide analogs for drug screening and nucleotide kits for a plethora of applications
Nucleosides Modified nucleoside analogs (i.e. nucleobase linked to a sugar moiety but lacking the phosphate groups)
In addition, with our pre-made building blocks and in-house expertise we manufacture even the most exotic nucleotide analog from the mg to kg scale in a Custom Synthesis, at conditions that are affordable even for academic customers. Find more information in the PDF file below:
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| Jena Bioscience is your #1 Reagent Supplier! | ||||||
Jena Bioscience is your one-stop-shop for all life science reagents. Check out our complete product portfolio at Jena Bioscience offers more than Nucleotide Analogs and Click Chemistry products: Macromolecular Crystallography accessories, Protein Expression products as well as Affinity Chromatography and Molecular Biology solutions make us your first choice for all life science consumables – at prices that will help to cut your costs significantly. |
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| Responsible for content / Imprint | ||||||
Jena Bioscience GmbH Loebstedter Str. 80 07749 Jena Germany Phone:+49 – 3641 – 6285 000 Fax: +49 – 3641 – 6285 100 E-Mail: info@jenabioscience.com Register Court: Amtsgericht Jena, HRB 207171 VAT No.: DE 195825742 Managing Directors: Thomas Billert Dr. Mathias Grün |
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