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   Significant Price Cut for Non-hydrolyzable Nucleotide Analogs!
   
       
       
  		    
   

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It is a pleasure for us to announce a significant price reduction for the non-hydrolyzable methyleno nucleotide analogs ApCpp, AppCp and GppCp. These analogs are widely used in purinoceptor research[1],[2], for biochemical studies on GTP-binding proteins[3], and for investigation of microtubules[4],[5].

Adenosine-5'-[(α,β)-methyleno]triphosphate (AMPCPP)
Cat.-No.: NU-421 		Adenosine-5'-[(β,γ)-methyleno]triphosphate (AMPPCP)
Cat.-No.: NU-422

Guanosine-5'-[(β,γ)-methyleno]triphosphate (GMPPCP)
Cat.-No.: NU-402


Now available as lyophilized solids in convenient pack sizes:

Product

Amount

Cat.-No.

Price (€)

ApCpp
(AMPCPP)

lyophilized – 10 mg

NU-421-10

162,50

lyophilized – 25 mg

NU-421-25

321,50

AppCp
(AMPPCP)

lyophilized – 10 mg

NU-422-10

43,50

lyophilized – 25 mg

NU-422-25

91,50

GppCp
(GMPPCP)

lyophilized – 5 mg

NU-402-5

37,50

lyophilized – 25 mg

NU-402-25

118,50


Please visit our complete portfolio of non-hydrolyzable nucleotide analogs at:

www.jenabioscience.com/cms/en/1/browse/227/

Selected references:
[1] Inscho (2001) Renal microvascular effects of P2 receptor stimulation. Clin. Exp. Pharm. Phys. 28:322.
[2] Dunn (2000) Fertility: Purinergic receptors and the male contraceptive pill. Curr. Biol. 10 (8):R305.
[3] Oswald et al. (2001) An increase in side chain entropy facilitates effector binding: NMR characterization of the side chain methyl group dynamics in Cdc42Hs. Biochem. 40 (15):4590.
[4] Salmon et al. (1997) How tubulin subunits are lost from the shortening ends of microtubules. J. Struct. Biol. 118:107.
[5] Dye et al. (1996) Assembly of microtubules from tubulin bearing the nonhydrolyzable guanosine triphosphate analogue GMPPCP [Guanylyl-5'-(β,γ-Methylenediphosphonate)]: variability of growth rates and the hydrolysis of GTP. Biochem. 35 (45):14331.


For questions and inquiries or if you require nucleotide analogs that are not on stock, please send us an e-mail at nucleotides@jenabioscience.com to receive a quote for a custom synthesis.


   
   

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