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   LEXSY – the eukaryotic protein expression system from Jena Bioscience
   
       
       
  		    
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If you are tired of

  • refolding recombinant protein from E. coli inclusion bodies...,

  • the slow growth of insect cell/Baculovirus cultures...,

  • tedious construction of mammalian expression cell lines...,

  • blown-up budgets due to expensive cell culture media and reagents...
... and all you need is a recombinant protein with correct post-translational modifications....



   
    ...THEN YOU SHOULD CHECK OUT LEXSY:
   

  • protein yields of up to 300 mg/L of culture.

  • fully eukaryotic protein expression and folding machinery with mammalian-type post-translational modifications.

  • easy to handle, fast growing and safe host: no specific labware, no cell biology equipment required.

  • simple construction of stable expression strains.

  • shuttle vectors: cloning in E. coli, expression in LEXSY host.

  • expression in three convenient configuations:
    constitutive, inducible, secretory.



    
    THE LEXSY HOST – LEISHMANIA TARENTOLAE
   


Leishmania tarentolae, a kinetoplast protozoan isolated from the Moorish gecko Tarentola mauretanica, does not infect mammals and can be kept in culture under S1 safety conditions.

   
    PROTEIN EXPRESSION WITH LEXSY – THREE TAILOR-MADE CONFIGURATIONS
   
Convenient expression kits for LEXSY protein production:

The LEXSYcon Kit permits efficient cytosolic expression combined with robustness and easy handling. The LEXSecrete Kit is most suitable for proteins that undergo post-translational modifications (PTMs) such as glycosylation or disulfide bond formation.

 The LEXSInduce Kit is recommended for cytotoxic proteins. Expression is efficiently regulated by the T7-TetR architecture, with very low background
LEXSYcon Expression Kit
contains vector pLEXSY-sat for constitutive expression		 LEXSecrete Expression Kit
contains vector pLEXSY_S-sat for secretory expression		 LEXSinduce Expression Kit
contains vector pLEXSY_I-neo and LEXSY host T7TR for inducible expression
EGE-1000 EGE-1100 EGE-1200
960 € 960 € 2250 €


   
    MORE LEXSY PRODUCTS – ALL YOU NEED FOR CLONING, EXPRESSION, STRAIN SELECTION, AND CULTIVATION
   

   
    LEXSY LICENSE – FOR COMMERCIAL USE OF THE EXPRESSION SYSTEM ONLY
   
The commercial use of LEXSY requires a license from Jena Bioscience. Academic and public institutions performing not-for profit research may use the LEXSY systems without any license.




Need further information? Please check out the LEXSY section at the Jena Bioscience website!

Or contact us by email at: expression@jenabioscience.com.


   
   

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Jena Bioscience GmbH
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Germany

Phone:+49 – 3641 – 6285 000
Fax: +49 – 3641 – 6285 100
E-Mail: info@jenabioscience.com

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Thomas Billert
Dr. Mathias Grün 		   
           
    http://www.jenabioscience.com   
           
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