Fluorescent nucleotide probes are important tools to study structure and function of proteins and nucleic acids. They are routinely used for:
- DNA microarray gene expression analysis
- fluorescence in situ hybridization (FISH)
- DNA sequencing
- single nucleotide polymorphism (SNP) analysis
- fluorescence imaging techniques at the single-molecule level
Selected literature citations:
Compound |
Aminoallyl-UTP-ATTO-680 ...more... |
Field of use |
Red dye labeling of RNA transcripts by in vitro T7 transcription |
Application |
Analysis of translational repression |
Reference |
Ephrussi et al. (2009) Drosophila PTB promotes formation of high-order RNP particles and represses oskar translation. Genes & Development 23:195. |
Compound |
EDA-GTP-5/6-TAMRA ...more... |
Field of use |
Yellow dye fluorescent probe |
Application |
Fluorescent probe to monitor GTPase activity of Rho and Ras proteins |
Reference |
Ahmadian et al. (2005) Monitoring the real-time kinetics of the hydrolysis reaction of guanine nucleotide-binding proteins. Biol. Chem. 386:1105. |
Nucleotide analogs not on stock may be available as custom synthesis, just send us an e-mail at nucleotides@jenabioscience.com with any questions you may have!
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