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Strong absorbtion, high luminescence, and high photostability make cyanines attractive dyes for Fluorescent in situ hybridization (FISH). Cy3-labeled DNA probes are widely used for determination of mRNA distribution on the cellular and subcellular level, monitoring gene expression, detecting gene deletions and translocations, detecting chromosome translocations and mapping and sequencing of genes.
Jena Bioscience has extended its large selection of fluorescent nucleotides by
CY3-LABELED NUCLEOTIDES!
For more detailed information, please check out our website at:
Selected references:
Quake et al. (2003) Sequence information can be obtained from single DNA molecules. PNAS 100 (7):3960. Waggoner et al. (1997) Stability, specificity and fluorescence brightness of multiply-labeled fluorescent DNA probes. Nucleic Acids Research 25 (14):2923. Waggoner et al. (1994) Cyanine dye dUTP analogs for enzymatic labeling of DNA probes. Nucleic Acids Research 22 (15):3226. Waggoner et al. (1990) Cyanine dye labeling reagents-carboxymethylindocyanine succinimidyl esters. Cytometry 11:418. Waggoner et al. (1989) Cyanine dye labeling reagents for sulfhydryl groups. Cytometry 10:3. Waggoner et al. (1989) Cyanine dye labeling reagents containing isothiocyanate groups. Cytometry 10:11.
For questions and inquiries or if you require nucleotide analogs that are not on stock, please send us an e-mail at nucleotides@jenabioscience.com to receive a quote for a custom synthesis.
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