Estradiol Glow is the ovarian steroid hormone 17-β-Estradiol labeled with a novel low molecular weight orange/red fluorophore, thus retaining its chemical properties and its biological activity. This allows for a wide range of applications including

• analysis of in vivo and in vitro steroid uptake in real time
• monitoring of intracellular and subcellular steroid transport
• studies on steroid-binding proteins
• use as tracer for steroid immunoassays (to replace isotopes or enzymes)
• photodynamic elimination of estrogen sensitive tissues and cells in experimental settings with possible future clinical implications

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[2] Vaasa et al. (2009) High-affinity bisubstrate probe for fluorescence anisotropy binding/displacement assays with protein kinases PKA and ROCK. Analytical Biochemistry 385(1):85.
[3] Enkvist et al. (2012) Protein-Induced Long Lifetime Luminescence of Nonmetal Probes. ACS chemical biology 6:1052.

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