Catalog GTP Signal Transduction - GAPs (GTPase Activation Proteins)GTP Signal Transduction - GAPs (GTPase Activation Proteins)
 
 
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G-proteins (heterotrimeric G-proteins and GTPases of the Ras superfamily) have only a low intrinsic GTPase activity. GTPase activating proteins (GAPs) accelerate the GTP hdrolysis reaction by up to 5 orders of magnitude, thus switching „off“ the activated GTPase and terminating the signaling activity. The malignant transformation of cells is often linked to oncogenic mutations of Ras that escape regulation by GAPs.
 

Product Accession No. Cat. No. Amount Price (EUR) Buy / Note Downloads
RapGAP-341 (R91A)
GTPase Activating Protein of Rap
human, recombinant, E. coli
NM_002885 PR-222 50 µg 180,00    Add this product to your notepad  

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