Catalog PI 3-Kinase Family - PI3KδPI 3-Kinase Family - PI3Kδ
 
 
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PI3Kα   |   PI3Kβ   |   PI3Kγ   |   PI3Kδ   |   Adaptor Proteins   |   Substrates   |   Inhibitors   |   PI3K Assay
 
PI 3-Kinase delta is expressed in endothelial and in white blood cells. Recently it was shown that the inactivation of PI3Kδ in bone marrow mast cells (BBMCs) leads to defective stem cell factor-mediated proliferation, adhesion and migration of these cells, and to impaired allergen-IgE-induced degranulation and cytokine release.
In neutrophils a role for PI3Kδ in TNFα-induced signalling was demonstrated by a reduction in Akt-phosphorylation and PDK1 activity upon treatment with the δ-specific inhibitor IC87114.
 

Product Accession No. Cat. No. Amount Price (EUR) Buy / Note Downloads
PI 3-Kinase δ GST
Phosphoinositide 3-Kinase δ GST, p110δGST/p85α
human, recombinant, Sf9 cells
O00329 PR-345 10 g 180,00    Add this product to your notepad  
p85 α
Phosphoinositide 3-Kinase regulatory subunit
bovine, recombinant, Leishmania tarentolae
NM_174575 PR-342 20 g 190,00    Add this product to your notepad  
p85 β
Phosphoinositide 3-Kinase regulatory subunit
bovine, recombinant, Sf9 cells
NP_777001.1 PR-942 10 g 190,00    Add this product to your notepad  

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