. . JBScreen Detergents, Screening Membrane Proteins, Macromolecular Crystallography, Products & Ordering, Jena Bioscience
 
 
Catalog Screening Membrane Proteins - JBScreen DetergentsScreening Membrane Proteins - JBScreen Detergents
 
 
JBScreen Detergents
JBScreen Detergents contain 4 x 24 unique detergents that are compatible with most common crystallization reagents and are therefore perfectly suited for membrane protein solubilization:
  • Ionic detergents
  • Non-ionic detergents
  • Zwitterionic detergents
  • Non-detergent Sulfobetaines
  • Synthetic Lipids
 
JBScreen Detergents can be used throughout the protein purification process or can be added afterwards by dialysis or ion-exchange chromatography (detergent exchange). Detergent exchange can be vital for obtaining well-diffracting membrane-protein crystals [1].
JBScreen Detergents is also valuable for additive screening with detergents and detergent mixtures [2,3] in combination with the JBScreen Membrane. This combination will enable you to screen a broad range of detergents, while concentrating on the most successful crystallization conditions, making crystallization screening of membrane proteins much more efficient and less time consuming.
 

JBScreen Detergents & Prometheus: A winning team
Screen for stabilizing detergents by combining JBScreen Detergents with Prometheus NT.48, a label-free nanoDSF technology developed by NanoTemper Technologies, ideally suited for membrane protein stabilization.
 

Product Cat. No. Amount Price (EUR) Buy / Note Downloads
JBScreen Detergents 1 CS-521 24 solutions
(250 Ál each)
150,00    Add this product to your notepad      
JBScreen Detergents 2 CS-522 24 solutions
(250 Ál each)
150,00    Add this product to your notepad      
JBScreen Detergents 3 CS-523 24 solutions
(250 Ál each)
150,00    Add this product to your notepad      
JBScreen Detergents 4 CS-524 24 solutions
(250 Ál each)
150,00    Add this product to your notepad      
JBScreen Detergents HTS CS-525 96 solutions
(250 Ál each)
450,00    Add this product to your notepad      
JBScreen Membrane 1 - 4 & JBScreen Detergents HTS CS-308 4 + 1 Kits 1.120,00    Add this product to your notepad

References

[1] Rosenow et al. (2003) The influence of detergents and amphiphiles on the solubility of the light harvesting complex. Acta Cryst. D59:1422
[2] Adir (1999) Crystallization of the oxygen-evolving reaction centre of photosystem II in nine different detergent mixtures. Acta Cryst. D55:891
[3] Koronakis et al. (2000) Crystal structure of the bacterial membrane protein TolC central to multidrug efflux and protein export. Nature 405:914
 


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