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  GTP Signal Transduction - GEFs (Guanine Nucleotide Exchange Factors)
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Small GTPases are normally membrane associated independently of their activation state. Interaction with a specific "guanidine exchange factor" (GEF) induces the GDP – GTP exchange and thereby activates the GTPase, allows for interaction with effector proteins, and localizes and/or activates these proteins.

Product Accession No. Cat. No. Amount Price (EUR) Buy Downloads
EPAC-1 ΔDEP
(Exchange Protein directly Activated by cAMP, lacks the Dishevelled, Egl-10 and Pleckstrin Domain)
Human, Recombinant, E. coli
O95398 PR-304 50 µg 180,00  
RCC1 (RanGEF)
(Regulator of Chromosome Condensation, Ran Guanine Exchange Factor)
Human, Recombinant, E. coli
BC010067 PR-306 50 µg 180,00  
RalGDS-RBDGST
Ras Binding Domain of the Ral Guanine Nucleotide Dissociation Stimulator
Human, Recombinant, E. coli
Recognized GTPases: Rap-1A, Rap-1B, Rap-2A, Rap-2B, Rit, Rin
NM_203365 PR-365 250 µg 180,00  


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