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  Other groups of Nucleotides - 6-Thio Guanosines and Inosines
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2'-Deoxy Uridines   |   3'-Deoxy Nucleotides   |   Phosphosulfates   |   Cyclic Nucleotides   |   Nucleoside Bisphosphates   |   CoA Derivatives   |   ara-Nucleotides   |   6-Modified Purines   |   7-Deaza Purines   |   Unmodified Purines   |   6-Thio Guanosines and Inosines   |   7-Methyl Guanosines   |   8-Oxo Guanosines   |   5-Methyl Cytidines and related   |   Other Nucleotide Analogs
 

6-Thio-GTP is a metabolite of Azathioprine, a drug used in the therapy of chronic inflammatory and auto-immune diseases. The immunosuppressive properties of Azathioprine are very likely caused by binding of 6-Thio-GTP to the GTPase Rac.

6-Methylthio-Guanosine, 6-Methylthio-Inosine and 6-Mercaptopurine-riboside nucleotides are structurally related to 6-Thio-GTP. 6-Mercaptopurine-riboside, a sulfhydryl analog of inosine, inhibits nucleoside transport across erythrocyte plasma membranes, and also has immunosuppressive properties. It has been used similarly to mercaptopurine in the treatment of leukemia.


Product Cat. No. Amount Price (EUR) Buy Downloads
6-Thio-GMP, S pack NU-1121S 150 Units 95,00  
6-Thio-GMP, L pack NU-1121L 750 Units 300,00  
6-Thio-GDP, S pack NU-1120S 50 Units 95,00  
6-Thio-GDP, L pack NU-1120L 250 Units 300,00  
6-Thio-GTP, S pack NU-1106S 150 Units 95,00  
6-Thio-GTP, L pack NU-1106L 750 Units 300,00  
6-Thio-GpCp, S pack
(6-Thio-GMPCP)
NU-417S 30 Units 95,00  
6-Thio-GpCp, L pack
(6-Thio-GMPCP)
NU-417L 150 Units 300,00  
6-Thio-GppCp, S pack
(6-Thio-GMPPCP)
NU-418S 50 Units 95,00  
6-Thio-GppCp, L pack
(6-Thio-GMPPCP)
NU-418L 250 Units 300,00  
6-Thio-GppNHp, S pack
(6-Thio-GMPPNP)
NU-419S 30 Units 95,00  
6-Thio-GppNHp, L pack
(6-Thio-GMPPNP)
NU-419L 150 Units 300,00  
6-Methylthio-GMP, S pack NU-1128S 100 Units 95,00  
6-Methylthio-GMP, L pack NU-1128L 500 Units 300,00  
6-Methylthio-GDP, S pack NU-1129S 50 Units 95,00  
6-Methylthio-GDP, L pack NU-1129L 250 Units 300,00  
6-Methylthio-GTP, S pack NU-1130S 100 Units 95,00  
6-Methylthio-GTP, L pack NU-1130L 500 Units 300,00  
6-Methylthio-IMP, S pack NU-1131S