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GTP Signal Transduction - GTPase Effectors
GDP-bound inactive G-proteins can be opened up by guanine nucleotide exchange factors (GEFs) causing the dissociation of GDP and the subsequent binding of GTP. This switches "on" the GTP signal transduction pathway alllowing the binding and activation of downstream effectors like ion channels or enzymes including adenylyl cyclases, kinases, and phosphatases.
| Product | Accession No. | Cat. No. | Amount | Price (EUR) | Buy | Downloads |
|---|---|---|---|---|---|---|
| RafRBD (c-Raf) Ras Binding Domain of Raf, c-Raf 1 Kinase human, recombinant, E. coli |
X03484, P04049 | PR-305 | 50 µg | 180,00 |  |
 |
| RafRBDGST (c-Raf) Ras Binding Domain of Raf, c-Raf 1 Kinase human, recombinant, E. coli |
X03484, P04049 | PR-366 | 500 µg | 180,00 | |
|
| RalGDS-RBDGST Ras Binding Domain of the Ral Guanine Nucleotide Dissociation Stimulator human, recombinant, E. coli Recognized GTPases: Rap-1A, Rap-1B, Rap-2A, Rap-2B, Rit, Rin |
NM_203365 | PR-365 | 250 µg | 180,00 | |
|
| RhotekinRBDGST Rhotekin Ras Binding Domain, from the Japanese human, recombinant, E. coli |
NM_033046 | PR-367 | 50 µg | 180,00 | |
|
| WASP-121GST Wiskott-Aldrich Syndrome Protein human, recombinant, E. coli Recognized GTPases: Cdc42, TC10,TCL |
U12707 | PR-369 | 250 µg | 180,00 | |
|
| EPAC-1 ΔDEP Exchange Protein directly Activated by cAMP, lacks the Dishevelled, Egl-10 and Pleckstrin Domain human, recombinant, E. coli |
O95398 | PR-304 | 50 µg | 180,00 | |
|
| AF6-RBDGST (residues 1-141) GTP-H-Ras binding cytoplasmic protein, Afadin - Ras-binding domain human, recombinant, E. coli |
NM_005936 | PR-398 | 50 µg | 180,00 | |
|
| RIN2-RAGST (residues 785-879) Ras and Rab interactor 2 - Ras-association domain human, recombinant, E. coli Recognized GTPases: TC21, M-Ras |
NM_018993 | PR-397 | 500 µg | 180,00 | |
|
For inquiries or further information, please contact us at proteins@jenabioscience.com