GTP Signal Transduction - Importins
Importins are involved in nuclear import and belong to a seperate class of Ran-GTP binding proteins. Importin α itself does not interact with nuclear pore complex (NPC) but functions as an adaptor that binds Importin β. Both these importins inhibit mitotic spindle assembly.
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human, recombinant, E. coli
D. melanogaster, recombinant, E. coli
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