Chemically modified pyrimidine nucleotides like 4-substituted pyrimidine nucleotide analogs are potential agonists of P2Y receptors for pharmacological studies.

The family of P2Y nucleotide receptors are important therapeutic targets including antithrombotic therapy, modulation of the immune system and cardiovascular system, inflammation, pain, diabetes, and treatment of cystic fibrosis and other pulmonary diseases. P2Y receptors are activated by adenine and/or uracil nucleotides.

1 Unit = 1 µl of a 10 mM solution.

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