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Other groups of Nucleotides - ara-Nucleotides |
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Ara-Nucleotides feature an opposite stereochemistry at the 2' carbon atom compared to ribo-nucleotides. They are incorporated into DNA by polymerases however, the DNA strand is only poorly elongated from the 3' ara-nucleotide residue and thus provides an opportunity for exonucleases to remove the ara-nucleotide.
Cytarabine (Cytosine arabinoside, ara-C) is a commonly used chemotherapy agent used mainly in the treatment of leukemia and non-Hodgkin lymphoma. It been shown to be misincorporated into DNA double helix, which has significant conformational consequences that affect the function of DNA.
Vidarabine (Adenosine arabinoside, ara-A) is an anti-viral drug which is active against herpes simplex and varicella zoster viruses.
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Product |
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Cat. No. |
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Amount |
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Price (EUR) |
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Buy |
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Downloads |
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ara-ATP, S pack
(Vidarabine triphosphate) |
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NU-1111S |
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50 Units |
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95,00 |
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ara-ATP, L pack
(Vidarabine triphosphate) |
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NU-1111L |
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250 Units |
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300,00 |
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ara-CDP, S pack
(Cytarabine diphosphate) |
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NU-1171S |
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50 Units |
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95,00 |
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ara-CDP, L pack
(Cytarabine diphosphate) |
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NU-1171L |
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250 Units |
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300,00 |
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ara-CTP, S pack
(Cytarabine triphosphate) |
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NU-1170S |
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100 Units |
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95,00 |
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ara-CTP, L pack
(Cytarabine triphosphate) |
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NU-1170L |
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500 Units |
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300,00 |
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