Catalog Protein Kinases and Deacetylases - Human SirtuinsProtein Kinases and Deacetylases - Human Sirtuins
 
 
Tyrosine Kinases   |   Tyrosine Like Kinases   |   Sterile 20 Serine/Threonine Kinases   |   Protein A, G and C Kinases   |   Calcium/Calmodulin-dependent Kinases   |   Cyclin-dependent Kinases   |   Substrate Peptides   |   Inhibitors   |   Human Sirtuins
 
human Sirtuins
Sirtuins are phylogenetically conserved from bacteria to humans and regulate cell functions beyond silencing. The proteins show a relevance to cancer, obesity, muscle differentiation, inflammation and neurodegeneration. In addition, Sirtuin activity may extend the lifespan of several organisms.
Human Sirtuins (class III protein deacetylases) utilize NAD+ as cosubstrate and act either as deacetylases or as ADP-ribosyltransferases.

Crystal structure of human Sirt5
in complex with an inhibitor
 

Product Cat. No. Amount Price (EUR) Buy / Note Downloads
Sirt3
Protein Deacetylase
human, recombinant, E. coli		 PR-170 50 µg 280,00    Add this product to your notepad  
Sirt5
Protein Deacetylase
human, recombinant, E. coli		 PR-171 200 µg 280,00    Add this product to your notepad  

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