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Protein Kinases and Deacetylases - Human Sirtuins |
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Sirtuins are phylogenetically conserved from bacteria to humans and regulate cell functions beyond silencing. The proteins show a relevance to cancer, obesity, muscle differentiation, inflammation and neurodegeneration. In addition, Sirtuin activity may extend the lifespan of several organisms.
Human Sirtuins (class III protein deacetylases) utilize NAD+ as cosubstrate and act either as deacetylases or as ADP-ribosyltransferases.
Crystal structure of human Sirt5
in complex with an inhibitor
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Amount |
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Price (EUR) |
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Buy |
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Downloads |
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Sirt3
Histone Deacetylase
human, recombinant, E. coli |
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PR-170 |
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50 µg |
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280,00 |
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Sirt5
Histone Deacetylase
human, recombinant, E. coli |
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PR-171 |
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200 µg |
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280,00 |
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