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More than 50 of the most prominent GPCRs as membrane suspensions ready-to-go for your research.

Adrenergic Receptors  |  Histamine Receptors  |  Leukotriene Receptors  |  Dopamine Receptors  |  Formyl Peptide Receptors  |  Complement Component 5a Receptors  |  Platelet-activating Factor Receptors  |  Cell Extracts


   Advantages and Applications of GPCRs in Sf9 Insect Cells

Simplified Illustration of GPCR-Classification

Click on the links in the scheme below to access the corresponding product pages:

Platelet-activating Factor ReceptorsComplement Component 5a ReceptorsFormyl Peptide ReceptorsHistamine ReceptorsDopamine ReceptorsLeukotriene ReceptorsAdrenergic Receptors


The superfamily of G-protein-coupled receptors (GPCRs) is the largest single class of receptors. In vertebrates, they are estimated to account for approximately 1% of the entire genome. Despite extremely diverse roles in the cell, all GPCRs share the structural hallmark of seven helical transmembrane domains. Most receptors are able to couple to and thus activate more than one G-protein subtype mediating the transduction of various signalling cascades.

GPCRs play key roles in a large number of physiological and pathophysiological conditions. Pathways involving GPCRs are the targets of hundreds of therapeutically useful drugs, including antihistamines, neuroleptics, antidepressants, and antihypertensives.


   More information on Jena Bioscience's GPCRs

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