Immobilized nucleotides provide a convenient and rapid purification procedure for a large number of proteins such as kinases, GTPases, chaperones, motor proteins and others.

Jena Bioscience offers affinity chromatography material that is tailor-made for purification (or for related assays) of particular (d)NTP-binding proteins since we produce NTPs and dNTPs that are linked to the matrix at various positions of sugar, base or phosphate moiety of the nucleotide, offer different types and lengths of linkers and provide different types of chromatography material ranging from bulk media to pre-packed columns that fit any machine.

Immobilized Adenosine Nucleotides:ATPdATPADPAMPcAMP
Affinity Chromatography Kits for
Adenosine Nucleotide binding Proteins
Immobilized Guanosine and m7Guanosine Nucleotides:GTPdGTPm7GTPm7GDPcGMP
Immobilized Cytidine Nucleotides:CTPdCTP
Immobilized Thymidine Nucleotides:dTTP
Immobilized Uridine Nucleotides:UTPdUTP
Immobilized Inosine Nucleotides:ITP
Immobilized Xanthosine Nucleotides:XTP

  Unmodified Agarose


Different types of chromatography material available

All our affinity chromatography materials carrying nucleotides or amino/phospho-amino acids are available as bulk media, pre-packed MPLC columns, syringe columns and screening columns. Please refer to the product pages to access the product lists and data sheets, and to order affinity chromatography products.

Affinity Chromatography - bulk AgaroseAffinity Chromatography - Syringe ColumnAffinity Chromatography - Screening ColumnsAffinity Chromatography - MPLC Column
Bulk mediaPre-packed syringe columnsPre-packed screening columnsPre-packed MPLC columns
based on Agarose
(equals Sepharose™ 4B)
based on Agarose
(equals Sepharose™ 4B)
based on Agarose
(equals Sepharose™ 4B)
  • maximum amount 0.6 ml
  • ready-to-use glass columns
  • one each upper and lower frit
  • upper and lower end piece
  • special 96-well-MTP format column holder on request
based on Toyopearl® AF-650M
  • 40 - 90 µ material
  • 1x Omnifit column kit 10x50 mm
  • 1x adjustable end piece
  • 2x female-female (1/4" to 6 mm) coupling
  • 2 m PTFE tubing (1/16" OD x 0.8 mm ID)
MPLC columns are delivered with adapters for FPLC Systems of BioRad, GE Healthcare (Äkta™) and Pharmacia.

Toyopearl® is a trademark of TOSOH Bioscience
Äkta™ and Sepharose™ are trademarks of GE Healthcare Companies

Please contact us at for more information.