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Cell Penetrating Peptides
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The internalization of bioactive cargo into live cells has become an area of fast growth. In particular, the use of Cell Penetrating Peptides (CPPs) as helper-molecules for overcoming cell membrane barriers enabled researchers to transfect numerous cell lines and cell types with a large number of proteins & enzymes, nucleotides, and nucleic acids.
In our CPP section we offer novel kits and formulations optimized for different types of cargo alongside with classic CPPs and auxiliary compounds for improving the internalization processes.
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Complete Internalization Kits
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Eveything you need for setting up an internalization experiment with your cell line of interest
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Internalization Cocktails and Cell Penetration Peptides
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Novel formulations for increased penetration alongside with classic CPPs
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Auxiliary Compounds
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Streamlined selection of reagents that help controlling and optimizing cell transfection experiments
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Cell Integrity Test Kits
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Test kits for checking suitability of cells for internalization of cargo
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Selected References
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- Handbook of Cell-Penetrating Peptides, Second Edition, Ed. by Ü. Langel, CRC Taylor and Francis, Boca Raton, London, New York (2007).
- Meade et al. (2008) Enhancing the cellular uptake of siRNA duplexes following non-covalent packaging with protein transduction domain peptides. Adv. Drug Deliv. Rev. 60:530.
- Prochiantz (2005) Protein transduction: from physiology to technology and vice versa. Adv. Drug Deliv. Rev. 57:491.
- Mäe et al. (2006) Cell-penetrating peptides as vectors for peptide, protein and oligonucleotide delivery. Curr. Opin. Pharmacol. 6:509.
- Deshayes et al. (2008) Delivery of proteins and nucleic acids using a non-covalent peptide-based strategy. Adv. Drug Deliv. Rev. 60:537.
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