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  GTP Signal Transduction - GTPase Effectors
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GDP-bound inactive G-proteins can be opened up by guanine nucleotide exchange factors (GEFs) causing the dissociation of GDP and the subsequent binding of GTP. This switches "on" the GTP signal transduction pathway alllowing the binding and activation of downstream effectors like ion channels or enzymes including adenylyl cyclases, kinases, and phosphatases.

Product Accession No. Cat. No. Amount Price (EUR) Buy Downloads
RafRBD (c-Raf)
Ras Binding Domain of Raf, c-Raf 1 Kinase
Human, Recombinant, E. coli
X03484, P04049 PR-305 50 µg 180,00  
RafRBDGST (c-Raf)
Ras Binding Domain of Raf, c-Raf 1 Kinase
Human, Recombinant, E. coli
X03484, P04049 PR-366 500 µg 180,00  
RalGDS-RBDGST
Ras Binding Domain of the Ral Guanine Nucleotide Dissociation Stimulator
Human, Recombinant, E. coli
Recognized GTPases: Rap-1A, Rap-1B, Rap-2A, Rap-2B, Rit, Rin
NM_203365 PR-365 250 µg 180,00  
RhotekinRBDGST
(Rhotekin Ras Binding Domain, from the Japanese
Human, Recombinant, E. coli
NM_033046 PR-367 50 µg 180,00  
WASP-121GST
Wiskott-Aldrich Syndrome Protein
Human, Recombinant, E. coli
Recognized GTPases: Cdc42, TC10,TCL
U12707 PR-369 250 µg 180,00  
EPAC-1 ΔDEP
(Exchange Protein directly Activated by cAMP, lacks the Dishevelled, Egl-10 and Pleckstrin Domain)
Human, Recombinant, E. coli
O95398 PR-304 50 µg 180,00  
AF6-RBDGST (residues 1-141)
(GTP-H-Ras binding cytoplasmic protein, Afadin - Ras-binding domain)
Human, Recombinant, E. coli
NM_005936 PR-398 50 µg 180,00  
RIN2-RAGST (residues 785-879)
Ras and Rab interactor 2 - Ras-association domain
Human, Recombinant, E. coli
Recognized GTPases: TC21, M-Ras
NM_018993 PR-397 1 mg 180,00  


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