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DNA Manipulation - Inhibition of DNA Methylation |
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5-Aza-dCTP, S pack
(Decitabine triphosphate) |
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NU-1118S |
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20 Units |
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98,50 |
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5-Aza-dCTP, L pack
(Decitabine triphosphate) |
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NU-1118L |
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100 Units |
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314,50 |
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Description
5-Aza-dCTP is an inhibitor of DNA methylation and antileukemic agent. It has been used to reactivate silent tumor suppressor
genes.
| Incorporation
DNA Polymerase alpha
References
Bouchard et al. (1983) Incorporation of 5-Aza-2'-deoxycytidine-5'-triphosphate into DNA. Interactions with mammalian DNA polymerase alpha and DNA methylase. Molecular Pharmacology 24 (1):109.
Lemaire et al. (2005) Enhancement of antineoplastic action of 5-aza-2'-deoxycytidine by zebularine on L1210 leukemia. Anti-Cancer Drugs 16 (3):301. |
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