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Au-flats™: The best Gold grids for Cryo-EM

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Au-flat™ is an ultrastable, biocompatible holey gold alloy film (80% Au and 20% Pd) with a thickness of ca. 45 nm supported by a TEM gold grid. Significant improvements have made Au-flats™ the new gold standard for Cryo-EM sample supports:

  • Supporting gold grids are ultra-flat with planar surface → resulting in an even ice thickness
  • Supporting gold grids are 60% thicker and have a 60% thicker rim (Figure 1) → improves strength and durability during handling and sample prep
  • Light color of Au-Pd film (Figure 2) → easy identification of the film side
  • Smaller grain size of the Au-Pd film → more accurate defocus during data collection
  • Optimized Au-Pd-film stress → maximize strength during sample prep and vitrification
  • Reduced beam induced motion → better imaging, quality and resolution

We have Au-flats™ in stock and they can be delivered within a few days!


Figure 1: Top view of new (left) and former (right) supporting grids.
Figure 1: Top view of new (left) and former (right) supporting grids.

Figure 2: The lighter color of the Au-Pd film (left) compared to the underlying gold mesh grid (right) allows for easy identification of the film side during sample preparation.
Figure 2: The lighter color of the Au-Pd film (left) compared to the underlying gold mesh grid (right) allows for easy identification of the film side during sample preparation.

Au-flats™: The following grids are available:

Cat. No. hole size hole spacing mesh
X-400-AU300 0.6 µm 1.0 µm 300 gold
X-401-AU300 1.2 μm 1.3 μm 300 gold
X-403-AU200 2.0 μm 2.0 μm 200 gold

Questions or inquiries?

Christin Reuter

E-mail Christin for technical inquiries or further information: xtals@jenabioscience.com